High-frequency Partial Liquid Ventilation in Two Infants

Partial liquid ventilation.

Correspondence: B. Lachmann, Dept of Anesthesiology (Room Ee 2393), Erasmus University Rotterdam, Postbox 1738, 3000 DR Rotterdam, The Netherlands. There is strong indication that modes of ventilation that lead to repeated closure and opening of surfactantdeficient alveoli can induce severe functional and histological lung damage [1]. New modes of ventilation are directed at prevention of lung ...

High-frequency partial liquid ventilation in respiratory distress syndrome: hemodynamics and gas exchange.

Partial liquid ventilation using conventional ventilatory schemes improves lung function in animal models of respiratory failure. We examined the feasibility of high-frequency partial liquid ventilation in the preterm lamb with respiratory distress syndrome and evaluated its effect on pulmonary and systemic hemodynamics. Seventeen lambs were studied in three groups: high-frequency gas ventilati...

Extended high-frequency partial liquid ventilation in lung injury: gas exchange, injury quantification, and vapor loss.

High-frequency oscillatory ventilation with perflubron (PFB) reportedly improves pulmonary mechanics and gas exchange and attenuates lung injury. We explored PFB evaporative loss kinetics, intrapulmonary PFB distribution, and dosing strategies during 15 h of high-frequency oscillation (HFO)-partial liquid ventilation (PLV). After saline lavage lung injury, 15 swine were rescued with high-freque...

High-Frequency Jet Ventilation of Infants and Children

Elective High-Frequency Oscillatory Ventilation Versus Conventional Ventilation for Acute Pulmonary Dysfunction in Preterm Infants

BACKGROUND Respiratory failure due to lung immaturity is a major cause of mortality in preterm infants. Although the use of intermittent positive pressure ventilation (IPPV) in neonates with respiratory failure saves lives, its use is associated with lung injury and chronic lung disease. A newer form of ventilation called high frequency oscillatory ventilation has been shown in experimental stu...